Hypothalamus is a small part in the middle of the brain between the pituitary gland and thalamus. It plays a major role in the production of hormones and stimulates other crucial functions in the body. Hypothalamic disease prevents the hypothalamus to function properly. Pituitary disease occurs when the pituitary gland produces a particular hormone in excess or in very less quantity. Mostly, these are caused by pituitary tumors which are non-cancerous in most of the cases.